OSMR Antibody (3E12)

Images

 
Western Blot: OSMR Antibody (3E12) [H00009180-M03] - Analysis of OSMR expression in transfected 293T cell line by OSMR monoclonal antibody (M03), clone 3E12. Lane 1: OSMR transfected lysatE (39.5 KDa). Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3E12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

OSMR Antibody (3E12) Summary

Immunogen
OSMR (NP_003990, 141 a.a. ~ 241 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.QDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP
Specificity
OSMR - oncostatin M receptor (3E12)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
OSMR
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for OSMR Antibody (3E12)

  • IL-31 receptor subunit beta
  • IL-31R subunit beta
  • IL-31RB
  • IL-31R-beta
  • Interleukin-31 receptor subunit beta
  • MGC150627
  • MGC75127
  • oncostatin M receptor
  • oncostatin-M specific receptor beta subunit
  • oncostatin-M-specific receptor subunit beta
  • OSMRBMGC150626

Background

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol OSMR
Entrez
Uniprot