OSCAR Antibody (18D440.1)

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Western Blot: OSCAR Antibody (18D440.1) [NB100-56679] - Western Blot analysis of Oscar using NB100-56679 at a 1:500 dilution against human spleen.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-56679
    • Availability
      Product Discontinued

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OSCAR Antibody (18D440.1) Summary

Immunogen
This monoclonal antibody was raised against a synthetic peptide containing amino acid residues of human Oscar protein.
Specificity
In human spleen, a 32 kDa band is observed.
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
OSCAR
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • Western Blot
Positive Control
Spleen Lysate (NB820-59259)

Reactivity Notes

Cross reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites with PBS and 0.2% Gelatin
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for OSCAR Antibody (18D440.1)

  • hOSCAR
  • MGC33613
  • OSCAR
  • osteoclast associated receptor OSCAR-S1
  • osteoclast associated receptor OSCAR-S2
  • osteoclast associated, immunoglobulin-like receptor
  • osteoclast-associated immunoglobulin-like receptor
  • Osteoclast-associated receptor
  • PIGR3
  • PIgR-3
  • Poly-Ig receptor 3
  • Polymeric immunoglobulin receptor 3

Background

Recently, a novel member of the leukocyte receptor complex (LRC)-encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional OSCAR Products

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Bioinformatics

Gene Symbol OSCAR
Entrez