Nucleotide binding protein like Antibody (2C8)

Images

 
Western Blot: Nucleotide binding protein like Antibody (2C8) [NBP2-01348] HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Nucleotide binding protein like (Right lane) cDNA for 48 ...read more
Flow Cytometry: Nucleotide binding protein like Antibody (2C8) [NBP2-01348] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by ...read more

Order Details


    • Catalog Number
      NBP2-01348
    • Availability
      Product Discontinued

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Nucleotide binding protein like Antibody (2C8) Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-250 of human NUBPL(NP_079428) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NUBPL
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Nucleotide binding protein like Antibody (2C8)

  • C14orf127
  • FLJ12660
  • huInd1IND1 homolog
  • IND1chromosome 14 open reading frame 127
  • iron-sulfur protein NUBPL
  • iron-sulfur protein required for NADH dehydrogenase
  • nucleotide binding protein-like
  • Nucleotide-binding protein-like

Background

This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. The respiratory complex I consists of 45 subunits and 8 iron-sulfur (Fe/S) clusters. This protein is an Fe/S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NUBPL
Entrez