Recombinant Human NTAL Protein

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SDS-Page: NTAL Protein [NBP1-44385] - NTAL, 26.2 kDa (238aa), confirmed by MALDI-TOF with a purity of 80% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human NTAL Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 27-243 of Human NTAL

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
LAT2
Purity
>80%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
26.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>80%, by SDS-PAGE

Alternate Names for Recombinant Human NTAL Protein

  • LAB
  • LABWilliams-Beuren syndrome chromosomal region 15 protein
  • Linker for activation of B-cells
  • linker for activation of T cells family, member 2
  • linker for activation of T-cells family member 2
  • Membrane-associated adapter molecule
  • Non-T-cell activation linker
  • NTAL
  • NTALWilliams-Beuren syndrome chromosomal region 5 protein
  • WBS15
  • WBSCR15
  • WBSCR5
  • WBSCR5HSPC046
  • Williams-Beuren syndrome chromosome region 5
  • WSCR5

Background

NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol LAT2
Entrez