Nogo Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      R-1017-100
    • Availability
      Product Discontinued

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Nogo Antibody Summary

Immunogen
A synthetic peptide (AMAKIQAKIPGLKRKAE) corresponding to a region (1176-1192) from the C-terminus of human NOGO-A. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Specificity
The specificity of this antibody has been confirmed by WB and IHC against the antigen.
Clonality
Polyclonal
Host
Rabbit
Gene
RTN4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1.0-2.0 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1.0-2.0 ug/ml
Application Notes
This antibody is useful in Immunohistochemistry and Western Blot. Human NOGO-A has a predicted length of 1192 residues and MW of 130 kDa.
Control
Nogo Knockout 293T Cell Lysate

Reactivity Notes

Cross reacts with Human, Mouse, Rat and Rabbit.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 mg DiSodium Phosphate, 0.9 mg NaCl and 5 mg BSA
Preservative
0.05% Sodium Azide
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized distilled water to a final concentration of 1.0 mg/ml. Centrifuge to remove any insoluble material.

Alternate Names for Nogo Antibody

  • ASY
  • foocen
  • Human NogoA
  • KIAA0886
  • My043 protein
  • Nbla00271
  • Nbla10545
  • neurite growth inhibitor 220
  • Neurite outgrowth inhibitor
  • Neuroendocrine-specific protein C homolog
  • Neuroendocrine-specific protein
  • NI220/250
  • Nogo protein
  • NOGO-A
  • Nogo-B
  • NOGOC
  • Nogo-C
  • NOGORTN4-B1
  • NSP
  • NSP-CL
  • reticulon 4
  • reticulon 5
  • reticulon-4
  • reticulon-5
  • RTN4-A
  • RTN4-B2
  • RTN4-C
  • RTN-x

Background

Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.



This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics Tool for Nogo Antibody (R-1017-100)

Discover related pathways, diseases and genes to Nogo Antibody (R-1017-100). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Nogo Antibody (R-1017-100)

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Pathways for Nogo Antibody (R-1017-100)

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Research Areas for Nogo Antibody (R-1017-100)

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Blogs on Nogo.

Nogo: A Promising Target for New Gene Therapies
Nogo is a neurite outgrowth inhibitor protein that plays an important role during central nervous system (CNS) development as well as in endoplasmic reticulum signaling regulation. Studies using Nogo antibodies have revealed Nogo proteins regulate...  Read full blog post.

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Bioinformatics

Gene Symbol RTN4
Uniprot