Recombinant Human Noggin Fc GMP Protein (NB3344-GMP)

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Bioactivity: Noggin Recombinant Protein (CF) [NB3344-GMP] - GMP-grade Recombinant Human Noggin Fc Chimera Inhibits BMP-4-induced alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for ...read more
SDS-Page: Noggin Recombinant Protein (CF) [NB3344-GMP] - 1 ug/lane of GMP-grade Recombinant Human Noggin Fc Chimera was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Format
CF

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Catalog# & Formulation Size Price

Recombinant Human Noggin Fc GMP Protein Summary

Description
Recombinant Human Noggin Fc Chimera GMP Protein, carrier free

Source: Mouse myeloma cell line, NS0-derrived

Amino Acid Info: Amino acid sequencing was blocked, suggesting it is consistent with Gln28 as the first N-terminal amino acid. Predicted N-terminal sequence: Gln28-His-Tyr-Leu-His-Ile-Arg-Pro-Ala-Pro
Details of Functionality
Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 ug/mL in the presence of 30 ng/mL of Recombinant Human BMP-4 (Catalog # 314-BP).
Protein/Peptide Type
Recombinant Protein
Gene
NOG
Endotoxin Note
<0.10 EU per 1 ug of the protein by the LAL method

Applications/Dilutions

Theoretical MW
49.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 3 months, -20 to -70 °C under sterile conditions after opening.
Buffer
0.2 um filtered solution in PBS
Reconstitution Instructions
Reconstitute at 100 ug/mL in PBS

Alternate Names for Recombinant Human Noggin Fc GMP Protein

  • NOG
  • Noggin
  • SYM1
  • symphalangism 1 (proximal)
  • synostoses (multiple) syndrome 1
  • SYNS1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol NOG
Entrez

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