NM23-H2/NME2 Antibody

Images

 
Western Blot: NM23-H2/NME2 Antibody [NB100-92047] - Analysis of NM23-H2/NME2 (H118) pAb at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate
Western Blot: NM23-H2/NME2 Antibody [NB100-92047] - Analysis of NME2 at 1:500 dilution. Lane 1 - HEK293T, Lane 2 - Raw264.7 whole cell lysate, Lane 3 - PC12 whole cell lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-92047
    • Availability
      Product Discontinued

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NM23-H2/NME2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 87-130 of Human NM23-H2.
Specificity
NME2 antibody detects endogenous levels of NDK B protein.
Clonality
Polyclonal
Host
Rabbit
Gene
NME2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500 - 1:1000
Theoretical MW
17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
NM23-H2/NME2 Lysate (NBL1-13684)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NM23-H2/NME2 Antibody

  • EC 2.7.13.3
  • Histidine protein kinase NDKB
  • MGC2212
  • NDK B
  • NDKB
  • NDP Kinase B2
  • NDPKB
  • NDPK-B
  • NM23B
  • NM23-H2
  • NME2
  • non-metastatic cells 2, protein (NM23B) expressed in
  • nucleoside diphosphate kinase B
  • protein (NM23) expressed in

Background

The nm23 protein is the collective designation for two closely related proteins encoded by the genes nm23H1 and nm23H2 now called NME1 and NME2. The protein is expressed in the nucleus and cytoplasm of all normal cells, and on the cell surface of many haematopoietic cells, including erythrocytes. Tumour cells with a high metastatic potential often lack or express only a low amount of nm23 protein, hence the nm23 protein has been described as a metastasis suppressor protein. Recent studies, however, suggest a more complex relationship between occurrence of the nm23 protein and metastatic activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional NM23-H2/NME2 Products

Bioinformatics Tool for NM23-H2/NME2 Antibody (NB100-92047)

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Diseases for NM23-H2/NME2 Antibody (NB100-92047)

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PTMs for NM23-H2/NME2 Antibody (NB100-92047)

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Bioinformatics

Gene Symbol NME2
Entrez
Uniprot