NKp46/NCR1 Antibody (n1D9)

Images

 
Flow Cytometry: NKp46/NCR1 Antibody (n1D9) [NBP1-04311] - Analysis of NKp46 in HeLa cell line, staining at2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. ...read more
Flow Cytometry: NKp46/NCR1 Antibody (n1D9) [NBP1-04311] - Flow cytometry analysis of NKp46 in PBMC, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat antimouse IgG Alexa fluor 488 conjugate. ...read more
Flow Cytometry: NKp46/NCR1 Antibody (n1D9) [NBP1-04311] - Profile of PBMC analzyed by flow cytometry.
Flow Cytometry: NKp46/NCR1 Antibody (n1D9) [NBP1-04311] - Profile of PBMC analyzed by flow cytometry

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
Clone
n1D9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

NKp46/NCR1 Antibody (n1D9) Summary

Immunogen
Recombinant human NKp46 protein
Specificity
Anti-NKp46, clone n1D9, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NKp46.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NCR1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
Application Notes
The antibody has been tested by immunofluorescent staining with flow cytometric analysis and by Western blot analysis to assure specificity and reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for NKp46/NCR1 Antibody (n1D9)

  • CD335 antigen
  • CD335
  • hNKp46
  • Ly94
  • LY94lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46)
  • Lymphocyte antigen 94 homolog
  • MAR-1
  • natural cytotoxicity triggering receptor 1
  • Natural killer cell p46-related protein
  • NCR1
  • NK cell-activating receptor
  • NKp46
  • NKP46FLJ99094
  • NK-p46lymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46)

Background

A natural cytotoxicity receptor (NCR), NKp46, is a glycoprotein that has two extracellular Ig-like domains followed by a about 40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NCR1
Uniprot