NGF R/TNFRSF16/p75NTR Antibody

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Western Blot: NGF R/TNFRSF16/p75NTR Antibody [NBP1-51183] - Extracts from HeLa cells

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51183
    • Availability
      Product Discontinued

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NGF R/TNFRSF16/p75NTR Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 251-300 of Human NGFR p75.
Specificity
p75NTR/NGF pAb detects endogenous levels of p75NTR/NGF protein.
Clonality
Polyclonal
Host
Rabbit
Gene
NGFR
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of CD271 (K279) pAb in extracts from HeLa cells
Theoretical MW
45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (approx. pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NGF R/TNFRSF16/p75NTR Antibody

  • CD271 antigen
  • CD271
  • Gp80-LNGFR
  • member 16
  • nerve growth factor receptor
  • NGF R
  • NGF receptor
  • NGFR
  • p75 ICD
  • p75 NTR
  • TNFRSF16
  • TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
  • tumor necrosis factor receptor superfamily member 16

Background

Nerve Growth Factor Receptor, also termed NGFR p75, p75NTR, or CD271 is the low affinity NGFR (LNGFR) which binds NGF and other neurotrophins including BDNF, NT3, NT4/5 with similar, low affinity. NGFR p75 is a 75kD transmembrane glycoprotein (399 a.a.) consisting of an extracellular domain (222 a.a.) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22 a.a.), and a cytoplasmic domain (155 a.a.). NGFR p75 is mainly expressed in Schwann cells and neurons and in a variety of non neuronal cells. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics Tool for NGF R/TNFRSF16/p75NTR Antibody (NBP1-51183)

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Bioinformatics

Gene Symbol NGFR
Entrez