NGF R/TNFRSF16/p75NTR Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-30625
    • Availability
      Product Discontinued

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NGF R/TNFRSF16/p75NTR Antibody Summary

Immunogen
A synthetic peptide from the cytoplasmic domain of human p75NTR (low affinity NGF receptor, p75, LNGFR, p75NTR) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including mouse and rat
Specificity
Appears to be specific for p75NTR.
Clonality
Polyclonal
Host
Rabbit
Gene
NGFR
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human, rat, mouse. Other species not yet tested.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water.

Alternate Names for NGF R/TNFRSF16/p75NTR Antibody

  • CD271 antigen
  • CD271
  • Gp80-LNGFR
  • member 16
  • nerve growth factor receptor
  • NGF R
  • NGF receptor
  • NGFR
  • p75 ICD
  • p75 NTR
  • TNFRSF16
  • TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
  • tumor necrosis factor receptor superfamily member 16

Background

FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Additional NGF R/TNFRSF16/p75NTR Products

Bioinformatics Tool for p75NTR/NGF Receptor Antibody (NBP1-30625)

Discover related pathways, diseases and genes to p75NTR/NGF Receptor Antibody (NBP1-30625). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for p75NTR/NGF Receptor Antibody (NBP1-30625)

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Pathways for p75NTR/NGF Receptor Antibody (NBP1-30625)

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PTMs for p75NTR/NGF Receptor Antibody (NBP1-30625)

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Bioinformatics

Gene Symbol NGFR
Entrez