Neuronostatin Antibody (2956E) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 2956E
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 594

Neuronostatin Antibody (2956E) [Alexa Fluor® 594] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Human Neuronostatin containing synthetic peptide
• Specificity: Detects a peptide specific for Neuronostatin in a region around amino acid 95 in Direct ELISA.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuronostatin Antibody (2956E) [Alexa Fluor® 594]

• Neuronostatin
• Neuronostatin-13
• NST
• preprosomatostatin
• prepro-somatostatin

Background

Neuronostatin is a 13-amino acid bioactive peptide hormone encoded by the somatostatin gene.  Neuronostatin has a widespread effect in the CNS and peripheral tissues.  It reduces food and water intake, increases mean arterial pressure, delays gastrointestinal transit, and increases glucagon secretion from pancreatic islet alpha cells among other things.  Neuronostatin is produced in the endocrine pancreas, specifically pancreatic beta cells. The amounts of immunoreactive neuronostatin are highest in spleen, pancreas, cerebrum, and hypothalamus but is also found in diverse tissues including the heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.