Neuroglycan C/CSPG5 Antibody

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Western Blot: Neuroglycan C/CSPG5 Antibody [NBP1-51343] - Extracts from THP1 and raw264.7 cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51343
    • Availability
      Product Discontinued

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Neuroglycan C/CSPG5 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 221-270 of Human Neuroglycan C.
Specificity
Neuroglycan C (W248) pAb detects endogenous levels of Neuroglycan C protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CSPG5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of Neuroglycan C (W248) pAb in extracts from THP1 and raw264.7 cells.
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Neuroglycan C/CSPG5 Antibody

  • CALEB
  • chondroitin sulfate proteoglycan 5 (neuroglycan C)
  • chondroitin sulfate proteoglycan 5
  • CSPG5
  • MGC44034
  • Neuroglycan C
  • NGC
  • NGCAcidic leucine-rich EGF-like domain-containing brain protein

Background

Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Additional Neuroglycan C/CSPG5 Products

Bioinformatics Tool for Neuroglycan C/CSPG5 Antibody (NBP1-51343)

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Diseases for Neuroglycan C/CSPG5 Antibody (NBP1-51343)

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Bioinformatics

Gene Symbol CSPG5
Entrez