NEIL1 Antibody

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

NEIL1 Antibody Summary

Immunogen
Recombinant full-length human NEIL1 protein
Localization
Nuclear
Specificity
NEIL1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NEIL1
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:500
Application Notes
WB: 1/1000. Predicted molecular weight: 44 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Positive Control
NEIL1 Lysate (NBL1-13579)
Publications
Read Publication using
NB600-1112 in the following applications:

  • WB
    1 publication

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 25172893) Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 20% Glycerol
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NEIL1 Antibody

  • DNA-(apurinic or apyrimidinic site) lyase Neil1
  • EC 3.2.2.-
  • EC 4.2.99.18
  • endonuclease 8-like 1
  • endonuclease VIII
  • Endonuclease VIII-like 1
  • FLJ22402
  • FPG1DNA glycosylase/AP lyase Neil1
  • hFPG1
  • NEH1
  • nei endonuclease VIII-like 1 (E. coli)
  • Nei homolog 1
  • NEI1
  • Nei-like protein 1

Background

Prokaryotes and lower eukaryotes possess activities that remove the plethora of oxidative DNA base damages produced during normal oxidative metabolism and which have been associated with cancer and aging. The availability of the human genome sequence has precipitated identification of human homologs of Escherichia coli Nei. Human NEIL1 is a DNA glycosylase, that phylogenetically belongs to the Fpg/Nei family, primarily found in the bacterial kingdom and is functionally homologous to bacterial Nei. Thymine glycol, a potentially lethal DNA lesion produced by reactive oxygen species, can be removed by DNA glycosylases. The NEIL1 gene is located on the long arm of chromosome 15 that is frequently deleted in human cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NEIL1 Antibody (NB600-1112)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.


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WB
(1)
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(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for NEIL1 Antibody (NB600-1112) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for NEIL1 Antibody (NB600-1112)

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Bioinformatics

Gene Symbol NEIL1
Entrez