Nectin-1/PVRL1 Antibody (6D12)

Images

 
Western Blot: PVRL1 Antibody (6D12) [NBP2-01197] HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Flow Cytometry: PVRL1 Antibody (6D12) [NBP2-01197] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PVRL1 antibody, and then analyzed ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-01197
    • Availability
      Product Discontinued

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Nectin-1/PVRL1 Antibody (6D12) Summary

Immunogen
Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PVRL1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Nectin-1/PVRL1 Antibody (6D12)

  • CD111 antigen
  • CD111
  • CLPED1ectodermal dysplasia 4 (Margarita Island type)
  • ED4
  • Herpes virus entry mediator C
  • Herpesvirus entry mediator C
  • Herpesvirus Ig-like receptor
  • HIgRPVRR
  • HVEC
  • HVECpoliovirus receptor-like 1
  • MGC142031
  • Nectin1
  • Nectin-1
  • OFC7nectin 1
  • poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • poliovirus receptor-related protein 1
  • PRR
  • PRR1
  • PRR1MGC16207
  • PVRL1
  • PVRR1
  • PVRR1nectin-1
  • SK-12

Background

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PVRL1
Entrez