NCAM-1/CD56 Antibody (MEM 188)

Images

 
Flow Cytometry: NCAM-1/CD56 Antibody (MEM 188) [NBP1-28394] - Analysis using the PE conjugate of NBP1-28394. Multiple staining of peripheral blood lymphocytes.
Flow (Cell Surface): NCAM-1/CD56 Antibody (MEM 188) [NBP1-28394] - Analysis using the FITC conjugate of NBP1-28394. Surface staining of human peripheral blood cells with anti-CD56 (MEM-188) FITC.

Product Details

Summary
Reactivity Hu, PoSpecies Glossary
Applications B/N, Flow, Flow-CS, IHC-Fr, ICC
Clone
MEM 188
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.1 mg/ml

Order Details

NCAM-1/CD56 Antibody (MEM 188) Summary

Immunogen
Acute myelogenous leukemia cell line KG-1
Specificity
Human CD56
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NCAM1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Blocking/Neutralizing 50-200 molar excess
  • Flow Cytometry < = 1 ug/10^6 cells
  • Immunohistochemistry-Frozen 1:10-1:500
  • Flow (Cell Surface)
  • Immunocytochemistry

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Alternate Names for NCAM-1/CD56 Antibody (MEM 188)

  • CD56 / NCAM-1
  • CD56 antigen
  • CD56
  • MSK39
  • NCAM1
  • N-CAM-1
  • NCAM-1
  • NCAMantigen recognized by monoclonal 5.1H11
  • neural cell adhesion molecule 1
  • neural cell adhesion molecule, NCAM

Background

CD56, an isoform of the neural cell adhesion molecule (NCAM), is a 220 kDa heavily glycosylated type I transmembrane protein. On human hematopoietic cells, its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial. (1-4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NCAM1
Entrez