Natriuretic Peptide Receptor B Antibody (1E4.)

Images

 
Western Blot: Natriuretic Peptide Receptor B Antibody (1E4) [H00004882-M02]
Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor B Antibody (1E4) [H00004882-M02] - Analysis of monoclonal antibody to NPR2 on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 1 ...read more
Sandwich ELISA: Natriuretic Peptide Receptor B Antibody (1E4) [H00004882-M02] - Detection limit for recombinant GST tagged NPR2 is 3 ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, PoSpecies Glossary
Applications WB, ELISA, IHC-P
Clone
1E4.
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Natriuretic Peptide Receptor B Antibody (1E4.) Summary

Immunogen
NPR2 (NP_003986.2, 131 a.a. - 230 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPL
Specificity
NPR2 (1E4)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NPR2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Natriuretic Peptide Receptor B Antibody (1E4.)

  • AMDM
  • ANPRB
  • atrial natriuretic peptide receptor type B
  • ECDM
  • GUC2B
  • GUCY2B
  • natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • NPRB
  • NPRBi

Background

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NPR2
Entrez
OMIM
Uniprot