Myosin Heavy Chain Antibody (BGN/04/4482)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-62781
    • Availability
      Product Discontinued

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Myosin Heavy Chain Antibody (BGN/04/4482) Summary

Immunogen
Native myosin heavy chain from muscle
Specificity
Muscle myosin is a hexameric protein that consists of two heavy chain subunits (MHC), two alkali light chain subunits (MLC) and two regulatory light chain subunits (MLC-2). This product was raised against rabbit myosin heavy chain but is also reported to cross react with human cardiac myosin.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MYH14
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:5000-1:20000

Reactivity Notes

Reacts with: Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
2.5 mg/ml
Purity
Protein A purified

Alternate Names for Myosin Heavy Chain Antibody (BGN/04/4482)

  • DFNA4
  • FLJ13881
  • FLJ43092
  • KIAA2034DKFZp667A1311
  • MHC16
  • MYH14 variant protein
  • MYH17
  • MYHC
  • Myosin heavy chain 14
  • Myosin Heavy Chain
  • Myosin heavy chain, non-muscle IIc
  • myosin
  • myosin, heavy chain 14
  • myosin, heavy chain 14, non-muscle
  • myosin, heavy polypeptide 14
  • myosin-14
  • NMHC II-C
  • NMHC-II-C
  • Non-muscle myosin heavy chain IIc
  • nonmuscle myosin heavy chain II-C

Background

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MYH14