Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) [Alexa Fluor® 647]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-44534AF647
    • Availability
      Product Discontinued

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Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) [Alexa Fluor® 647] Summary

Immunogen
Recombinant human MYH11 protein (MYH11/923); Human uterus extract (SMMS-1)
Localization
Cytoplasmic
Marker
Leiomyosarcoma & Myoepithelial Cell Marker
Specificity
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
MYH11
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human, Rat. Predicted to have broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1) [Alexa Fluor® 647]

  • AAT4
  • FAA4
  • MYH11 myosin, heavy chain 11, smooth muscle
  • MYH11
  • SMHC
  • SMMHC
  • Smooth muscle myosin heavy chain

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MYH11