Myosin Antibody (TH22 (BGN/04/4422))



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Product Discontinued
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Myosin Antibody (TH22 (BGN/04/4422)) Summary

Native myosin heavy chain from muscle
Muscle myosin is a hexameric protein that consists of two heavy chain subunits (MHC), two alkali light chain subunits (MLC) and two regulatory light chain subunits (MLC-2). This product is specific for rabbit myosin heavy chain.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline
0.09% Sodium Azide
1.0 mg/ml
Protein G purified

Reactivity Notes



Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Blogs on Myosin.

Myosin Molecular Motor of Membrane Cargo
The Myosin superfamily is a large and diverse protein family, and its members are grouped into many classes, are involved in a number of cellular pathways (1). Myosins contain actin- and ATP-binding sites in their conserved catalytic head domain and l...  Read full blog post.

Using Myosin Antibodies for Tumor Identification
Myosin is a super family of actin based molecular motors that hydrolyze ATP and generate physical force to move specific molecules inside the cell. This super family, divided into at least twenty four classes based on head domain sequence similarity a...  Read full blog post.

Myosin is More than Just a Heavy Lifter
Myosin is a well-known, hexameric molecular motor that is a key cytoskeletal component. It consists of a pair of myosin heavy chain subunits (MHC), a pair of essential myosin light chain subunits (MLC), and a pair of regulatory light chain subunits (R...  Read full blog post.

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Product PDFs


Gene Symbol MYH14

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