Myocilin Antibody

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Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-40064] - Analysis of anti-MYOC antibody with human eye, retina at concentration 5 ug/ml.

Product Details

Summary
Product Discontinued
View other related Myocilin Primary Antibodies

Order Details


    • Catalog Number
      NBP1-40064
    • Availability
      Product Discontinued

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Myocilin Antibody Summary

Immunogen
Synthetic peptide from human MYOC.
Specificity
KLH conjugated synthetic peptide comprising amino acids 69 - 85 [SVIHNLQRDSSTQRLDL] of the human myocilin (MYOC) protein.
Predicted Species
Primate (100%), Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYOC
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA 1:1000
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for Myocilin Antibody

  • GLC1A
  • GLC1Amyocilin
  • GPOA
  • JOAG
  • JOAG1
  • MYOC
  • Myocilin
  • myocilin, trabecular meshwork inducible glucocorticoid response
  • TIGR
  • TIGRmutated trabecular meshwork-induced glucocorticoid response protein
  • Trabecular meshwork-induced glucocorticoid response protein

Background

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MYOC
Entrez
Uniprot