Western Blot: Myocilin Antibody (4F8) [H00004653-M01] - Analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M01), clone 4F8.Lane 1: MYOC transfected lysate(57 KDa).Lane 2: ...read more
Immunohistochemistry-Paraffin: Myocilin Antibody (4F8) [H00004653-M01] - Analysis of monoclonal antibody to MYOC on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 3 ug/ml.
Western Blot: Myocilin Antibody (4F8) [H00004653-M01] - Analysis of MYOC over-expressed 293 cell line, cotransfected with MYOC Validated Chimera RNAi ( Cat # H00004653-R01V ) (Lane 2) or non-transfected control (Lane ...read more
Immunoprecipitation: Myocilin Antibody (4F8) [H00004653-M01] - Analysis of MYOC transfected lysate using anti-MYOC monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MYOC MaxPab rabbit polyclonal ...read more
ELISA: Myocilin Antibody (4F8) [H00004653-M01] - Detection limit for recombinant GST tagged MYOC is approximately 0.3ng/ml as a capture antibody.
MYOC (AAH29261, 36 a.a. - 135 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQT
TIGRmutated trabecular meshwork-induced glucocorticoid response protein
Trabecular meshwork-induced glucocorticoid response protein
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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