MVK Antibody [Unconjugated]

Images

 
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, A431 human epithelial carcinoma cell line, and HEK001 human epidermal keratinocyte cell line. PVDF membrane was probed with 0.1 µg/mL of ...read more
MVK was detected in immersion fixed A431 human epithelial carcinoma cell line using Rabbit Anti-Human MVK Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8516) at 2 µg/mL for 3 hours at room temperature. ...read more
MVK was immunoprecipitated from 400 µg of HepG2 human hepatocellular carcinoma cell line and A431 human epithelial carcinoma cell line lysates using 4 µg of Rabbit Anti-Human MVK Antigen Affinity-purified Polyclonal ...read more
Simple Western lane view shows lysates of HepG2 human hepatocellular carcinoma cell line and HEK001 human epidermal keratinocyte cell line, loaded at 0.2 mg/mL. A specific band was detected for MVK at approximately ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western, IP, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price

MVK Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human MVK
Met1-Lys396
Accession # Q03426
Specificity
Detects human MVK in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MVK
Purity
Immunogen affinity purified
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • Simple Western 1 ug/mL
  • Immunoprecipitation 4 ug/mL
  • Immunocytochemistry 5-15 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MVK Antibody [Unconjugated]

  • EC 2.7.1.36
  • LH receptor mRNA-binding protein
  • LRBP
  • mevalonate kinase (mevalonic aciduria)
  • mevalonate kinase 1
  • mevalonate kinase
  • Mevalonic Aciduria
  • MKFLJ96772
  • MVK
  • MVLK
  • POROK3

Background

MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family, Mevalonate kinase subfamily of proteins. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.Over aa 1-396, human MVK shares 81% aa identity with mouse MVK.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF-258-PB
Species: Hu
Applications: WB, Simple Western, IHC
AF-252-PB
Species: Hu
Applications: WB, IHC
NB600-1071
Species: Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NBP1-97765
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP1-84579
Species: Hu
Applications: IHC, IHC-P
NB100-62346
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
NBP1-83142
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-66888
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IP
NBP2-17262
Species: Hu
Applications: WB, ICC/IF
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Flow-IC
AF1513
Species: Mu
Applications: WB, Simple Western, Flow, IHC, IP, CyTOF-ready
NBP2-45041
Species: Hu, Po
Applications: Flow, IHC, IHC-Fr, IF

Publications for MVK Antibody (AF8516) (0)

There are no publications for MVK Antibody (AF8516).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for MVK Antibody (AF8516) (0)

There are no reviews for MVK Antibody (AF8516). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MVK Antibody (AF8516) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional MVK Products

Bioinformatics Tool for MVK Antibody (AF8516)

Discover related pathways, diseases and genes to MVK Antibody (AF8516). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MVK Antibody (AF8516)

Discover more about diseases related to MVK Antibody (AF8516).
 

Pathways for MVK Antibody (AF8516)

View related products by pathway.

PTMs for MVK Antibody (AF8516)

Learn more about PTMs related to MVK Antibody (AF8516).

Blogs on MVK

There are no specific blogs for MVK, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MVK Antibody [Unconjugated] and receive a gift card or discount.

Bioinformatics

Gene Symbol MVK
Uniprot