MSK1/RPS6KA5 Antibody

Images

 
Western Blot: MSK1/RPS6KA5 Antibody [NBP1-51315] - Extracts from mouse brain cells.
Immunohistochemistry-Paraffin: MSK1/RPS6KA5 Antibody [NBP1-51315] - Paraffin-embedded human breast carcinoma tissue at 1:50.
Immunohistochemistry-Paraffin: MSK1/RPS6KA5 Antibody [NBP1-51315] - Human colon carcinoma tissue.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51315
    • Availability
      Product Discontinued

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MSK1/RPS6KA5 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 181-230 of Human MSK1.
Specificity
MSK1 (D205) pAb detects endogenous levels of MSK1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
RPS6KA5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of MSK1 (D205) pAb in extracts from mouse brain cells.
Immunohistochemistry (IHC) analyzes of MSK1 (D205) pAb in paraffin-embedded human colon carcinoma tissue.
Theoretical MW
90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MSK1/RPS6KA5 Antibody

  • EC 2.7.11
  • MGC1911,90 kDa ribosomal protein S6 kinase 5
  • MSK1
  • MSK1EC 2.7.11.1
  • MSPK1
  • Nuclear mitogen- and stress-activated protein kinase 1
  • ribosomal protein S6 kinase alpha-5
  • ribosomal protein S6 kinase, 90kD, polypeptide 5
  • ribosomal protein S6 kinase, 90kDa, polypeptide 5
  • RLPK
  • RPS6KA5
  • RSKL
  • RSK-like protein kinase
  • S6K-alpha-5

Background

The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, have been implicated as important signaling intermediates in response to a broad range of ligand-activated receptor tyrosine kinases. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. A related S6 kinase, p70 S6 kinase, functions to phosphorylate the S6 protein on ribosomal 40S subunits. p70 S6 kinase beta shares high sequence homology with p70 S6 kinase,except in the carboxy terminus where it contains a proline-rich domain that may be involved in SH3 domain containing protein interactions. MSK1 (also designated RLPK) is related to Rsk and p70 S6 kinase family members and is thought to be structurally similar to Rsk family members, but it may be regulated by distinct mechanisms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics Tool for MSK1/RPS6KA5 Antibody (NBP1-51315)

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Diseases for MSK1/RPS6KA5 Antibody (NBP1-51315)

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PTMs for MSK1/RPS6KA5 Antibody (NBP1-51315)

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Bioinformatics

Gene Symbol RPS6KA5
Entrez