MMP23 Antibody

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Western Blot: MMP23 Antibody [NB100-91877] - Analysis of MMP-23 (V371) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate
Western Blot: MMP23 Antibody [NB100-91877] - Analysis of MMP23 (V371) antibody in extracts from SKOV3 cells.

Product Details

Summary
Product Discontinued
View other related MMP23 Primary Antibodies

Order Details


    • Catalog Number
      NB100-91877
    • Availability
      Product Discontinued

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MMP23 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 341-390 of Human MMP-23.
Clonality
Polyclonal
Host
Rabbit
Gene
MMP23A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of MMP-23 (V371) pAb in extracts from SKOV3 cells.
Theoretical MW
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MMP23 Antibody

  • EC 3.4.24.-
  • Femalysin
  • matrix metallopeptidase 23A (pseudogene)
  • matrix metallopeptidase 23A
  • matrix metalloproteinase 23A
  • Matrix metalloproteinase-21
  • Matrix metalloproteinase-22
  • MIFR-1
  • MIFRMMP-21
  • MMP21MMP-22
  • MMP22
  • MMP-23

Background

Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear. A dramatic switch in MMP-23 mRNA localization from granulosa cells to theca-externa/ fibroblasts and ovarian surface epithelium occurs during follicular development. MMP-23 is expressed in ovary, testis and prostate, suggesting that MMP-23 plays a specialized role in the reproductive processes. The human MMP-23 gene maps to chromosome 1p36.3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MMP23A
Entrez