MMP-9 Antibody

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Western Blot: MMP9 Antibody [NBP1-50744]

Product Details

Summary
Product Discontinued
View other related MMP-9 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-50744
    • Availability
      Product Discontinued

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MMP-9 Antibody Summary

Immunogen
E. coli-expressed recombinant human MMP-9
Clonality
Polyclonal
Host
Rabbit
Gene
MMP9
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
The antibody can be used in Western Blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Recombinant human MMP-9 can be used as a positive control.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 0.5% BSA, 5mM EDTA and 30% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MMP-9 Antibody

  • 92 kDa gelatinase
  • 92 kDa type IV collagenase
  • CLG4B
  • EC 3.4.24
  • EC 3.4.24.35
  • Gelatinase B
  • GELB
  • macrophage gelatinase
  • MANDP2
  • matrix metallopeptidase 9
  • matrix metalloproteinase 9
  • matrix metalloproteinase-9
  • MMP9
  • MMP-9
  • type V collagenase

Background

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9 contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to be useful for western blotting and immunohistochemistry of human MMP9. MMP2, MMP9, Fibronectin 1, Nidogen 1, Integrin a5, Integrin a2, Matrilin 2, Bone morphogenic protein 1, PDGFb, FGF7, CD44, CD36, Collagen, type VII, alpha 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for MMP-9 Antibody (NBP1-50744)

Discover related pathways, diseases and genes to MMP-9 Antibody (NBP1-50744). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for MMP-9 Antibody (NBP1-50744)

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Research Areas for MMP-9 Antibody (NBP1-50744)

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Blogs on MMP-9.

Cytokeratin 18 - A Intermediate Filament Cyotskeletal Component
Keratins, also called cytokeratins, are a family of filamentous structural proteins that form the intermediate filaments within epithelial cells. Keratins are differentially expressed depending on both the epithelial cell origin and degree of differen...  Read full blog post.

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Bioinformatics

Gene Symbol MMP9
Entrez
Uniprot