MMP-3 Antibody Summary
MMP3 (NP_002413.1, 1 a.a. ~ 477 a.a) full-length human protein.
Mesenchymal Cells Marker
Protein G purified
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Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Protein G purified
This antibody is useful for Western Blot
This product is reactive against Human.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for MMP-3 Antibody
- EC 3.4.24
- EC 188.8.131.52
- matrix metallopeptidase 3 (stromelysin 1, progelatinase)
- matrix metalloproteinase 3 (stromelysin 1, progelatinase)
- Matrix metalloproteinase-3
- Stromelysin 1
Effective inhibitors of matrix metalloproteinases (MMPs), a family of connective tissue-degrading enzymes, could be useful for the treatment of diseases such as cancer, multiple sclerosis, and arthritis (1). Matrix metalloproteinase-3 (MMP-3) is a protein involved in tumor invasion and metastasis. MMP3 (stromelysin) is a secreted metalloprotease with a wide range of substrate specificities. MMP3 is synthesized in a preproenzyme form with a calculated size of 54 kDa and a 17-amino acid long signal peptide. Data indicate that the expression and the possible involvement of secreted metalloproteases in tumorigenesis result from a specific interaction between the transforming factor and the target cell, which may vary in different species (2). In neural studies, matrix metalloproteinase-3 (MMP-3) was newly induced and activated in stressed dopamine cells, and the active form of MMP-3 (actMMP-3) was released into the medium. The released actMMP-3, as well as catalytically active recombinant MMP-3 (cMMP-3) led to microglial activation and superoxide generation in microglia and enhanced DA cell death. (3).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Additional MMP-3 Antibody Products
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Bioinformatics Tool for MMP-3 Antibody (H00004314-B01P)
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