MMP-3 Antibody (F36P1B4)

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Western Blot: MMP-3 Antibody (F36P1B4) [NB100-78555] - Analysis of recombinant human MMP-3 protein using anti-MMP-3, clone F36P1B4.

Product Details

Summary
Product Discontinued
View other related MMP-3 Primary Antibodies

Order Details


    • Catalog Number
      NB100-78555
    • Availability
      Product Discontinued

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MMP-3 Antibody (F36P1B4) Summary

Immunogen
Ovalbumin-conjugated synthetic peptide CKSLRKLEPELH
Marker
Mesenchymal Cells Marker
Specificity
MMP3 (F36P1B4)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MMP3
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
Application Notes
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 mug per 5 ml antibody dilution buffer for each mini-gel.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for MMP-3 Antibody (F36P1B4)

  • CHDS6
  • EC 3.4.24
  • EC 3.4.24.17
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • matrix metalloproteinase 3 (stromelysin 1, progelatinase)
  • Matrix metalloproteinase-3
  • MGC126102
  • MGC126103
  • MMP3
  • MMP-3
  • proteoglycanase
  • SL-1
  • STMY
  • STMY1MGC126104
  • STR1
  • Stromelysin 1
  • stromelysin-1
  • transin-1

Background

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP3 degrades fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP3 is thought to play a prominent role in the pathogenesis of rheumatoid arthritis. Clone F36P1B4 has been shown to be useful for western blotting, ELISA and immunohistochemistry of human MMP3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional MMP-3 Products

Bioinformatics Tool for MMP-3 Antibody (NB100-78555)

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Diseases for MMP-3 Antibody (NB100-78555)

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Pathways for MMP-3 Antibody (NB100-78555)

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PTMs for MMP-3 Antibody (NB100-78555)

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Research Areas for MMP-3 Antibody (NB100-78555)

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Blogs on MMP-3.

MMP3 - a potential target for arthritis therapies
Matrix metalloproteinases (MMPs) are responsible for the degradation of extracellular matrix proteins. MMPs are essential for tissue remodeling during normal processes such as embryonic development as well as pathological conditions such as arthri...  Read full blog post.

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Bioinformatics

Gene Symbol MMP3
Entrez