MMP-3 Antibody (F36P1B4) Summary
Ovalbumin-conjugated synthetic peptide CKSLRKLEPELH
Mesenchymal Cells Marker
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS [pH 7.2]
0.09% Sodium Azide
Protein A or G purified
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 mug per 5 ml antibody dilution buffer for each mini-gel.
Alternate Names for MMP-3 Antibody (F36P1B4)
- EC 3.4.24
- EC 184.108.40.206
- matrix metallopeptidase 3 (stromelysin 1, progelatinase)
- matrix metalloproteinase 3 (stromelysin 1, progelatinase)
- Matrix metalloproteinase-3
- Stromelysin 1
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP3 degrades fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP3 is thought to play a prominent role in the pathogenesis of rheumatoid arthritis. Clone F36P1B4 has been shown to be useful for western blotting, ELISA and immunohistochemistry of human MMP3.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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