MMP-11 Antibody Summary
Synthetic peptide, corresponding to amino acids 55-100 of Human MMP-11.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, pH 7.2
15mM Sodium Azide
Immunogen affinity purified
- Western Blot 1:500-1:1000
- Immunocytochemistry/Immunofluorescence 1:50-1:200
- Immunohistochemistry 1:50-1:200
- Immunohistochemistry-Paraffin 1:50-1:200
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Alternate Names for MMP-11 Antibody
- EC 3.4.24
- EC 3.4.24.-
- EC 220.127.116.11
- matrix metallopeptidase 11 (stromelysin 3)
- matrix metalloproteinase 11 (stromelysin 3)
- Matrix metalloproteinase-11
- STMY3stromelysin 3
- stromelysin III
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin- 1, -2 and -3) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and it is expressed at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Applications: WB, IHC, IHC-P
Applications: WB, IHC
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
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Additional MMP-11 Antibody Products
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MATRIX METALLOPROTEINASE 11
, MATRIX METALLOPROTEINASE 2
, MATRIX METALLOPROTEINASE 3
, MATRIX METALLOPROTEINASE 7
, MATRIX METALLOPROTEINASE 9
, STROMELYSIN 3
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