MMP-11 Antibody

Images

 
Western Blot: MMP-11 Antibody [NB100-91870] - 11 (G88) pAb in extracts from raw264.7 cells.
Immunohistochemistry-Paraffin: MMP-11 Antibody [NB100-91870] - Human breast carcinoma tissue.
Western Blot: MMP-11 Antibody [NB100-91870] - Analysis of MMP-11 (G88) antibody in extracts from A549 cells.

Product Details

Summary
Product Discontinued
View other related MMP-11 Primary Antibodies

Order Details


    • Catalog Number
      NB100-91870
    • Availability
      Product Discontinued

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MMP-11 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 55-100 of Human MMP-11.
Clonality
Polyclonal
Host
Rabbit
Gene
MMP11
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MMP-11 Antibody

  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.24
  • matrix metallopeptidase 11 (stromelysin 3)
  • matrix metalloproteinase 11 (stromelysin 3)
  • Matrix metalloproteinase-11
  • MMP11
  • MMP-11
  • SL-3
  • ST3
  • STMY3stromelysin 3
  • stromelysin III
  • stromelysin-3

Background

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin- 1, -2 and -3) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and it is expressed at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MMP-11 Antibody (NB100-91870) (0)

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Secondary Antibodies

 

Isotype Controls

Additional MMP-11 Products

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Discover related pathways, diseases and genes to MMP-11 Antibody (NB100-91870). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for MMP-11 Antibody (NB100-91870)

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PTMs for MMP-11 Antibody (NB100-91870)

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol MMP11
Entrez
Uniprot