MMP-11 Antibody (SL3.05)

Images

 
Immunohistochemistry: MMP11 Antibody (SL3.05) [NB120-4102] - Formalin-fixed, paraffin-embedded human placenta stained with MMP-11 (Cat NB 120-4102) using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining ...read more
Immunohistochemistry-Paraffin: MMP11 Antibody (SL3.05) [NB120-4102] - Formalin fixed paraffin embedded human placenta stained with MMP-11 antibody.

Product Details

Summary
Product Discontinued
View other related MMP-11 Primary Antibodies

Order Details


    • Catalog Number
      NB120-4102
    • Availability
      Product Discontinued

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MMP-11 Antibody (SL3.05) Summary

Immunogen
Recombinant protein corresponding to active form of human MMP 11.
Localization
Secreted
Specificity
This detects a protein of 60 kDa (latent), 47 kDa (active) and 35 kDa (degradation product).
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MMP11
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1-2 ug/ml
Application Notes
For formalin fixed paraffin embedded sections no special pre-treatment is required.

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.66 mg/ml
Purity
Protein A or G purified

Alternate Names for MMP-11 Antibody (SL3.05)

  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.24
  • matrix metallopeptidase 11 (stromelysin 3)
  • matrix metalloproteinase 11 (stromelysin 3)
  • Matrix metalloproteinase-11
  • MMP11
  • MMP-11
  • SL-3
  • ST3
  • STMY3stromelysin 3
  • stromelysin III
  • stromelysin-3

Background

Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Diseases for MMP-11 Antibody (NB120-4102)

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Bioinformatics

Gene Symbol MMP11
Entrez