MKK6/MEK6 [p Ser207, p Thr211] Antibody

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      NBP1-48873
    • Availability
      Product Discontinued

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MKK6/MEK6 [p Ser207, p Thr211] Antibody Summary

Immunogen
This antibody was generated by immunizing host with Recombinant (partial), N-terminal
Modification
p Ser207, p Thr211
Localization
MKK6 (only heart), MKK6B muscle, heart, liver, pancreas
Specificity
This antibody has been tested to recognize phosphorylated and nonphosphorylated forms. Post translational modifications exist on sites Ser 207/Thr 211.The modifications consist of Phosphorylation.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP2K6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 μl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Reactivity Notes

Mouse, Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MKK6/MEK6 [p Ser207, p Thr211] Antibody

  • MAP kinase kinase 6
  • MAP2K6
  • MAPK/ERK kinase 6
  • MAPKK6dual specificity mitogen-activated protein kinase kinase 6
  • MEK6
  • MEK6MAPKK 6
  • mitogen-activated protein kinase kinase 6
  • MKK6
  • MKK6MEK 6
  • PRKMK6
  • PRKMK6protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
  • SAPKK3
  • SAPKK3EC 2.7.12.2

Background

MKK6 (Mitogen-activated protein kinase 6, MAPK/ERK kinase 6) is a 37 kD serine/threonine kinase family, MAP kinase subfamily. Two isoforms of MKK6 have been reported; MKK6 (only heart), MKK6B muscle, heart, liver, and pancreas. MKK6 phosphorylates and activates MAP kinase p38 and stress-activated kinase JNK. MKK6 is activated by UV, anisomycin, and osomotic shock. MKK6 is phosphorylated (Ser 207/Thr 211). MKK6 has been shown to interact with ASK-1 kinase. The Poly6047 antibody recognizes the N-terminal region of both human and mouse MKK6 and has been shown to be useful for Western blotting. Interacts with ASK-1 kinase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MAP2K6
Entrez