MKK4/MEK4 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

MKK4/MEK4 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-MAP2K4 full-length
Gene
MAP2K4

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for MKK4/MEK4

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-MAP2K4 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MKK4/MEK4 Overexpression Lysate (Denatured)

  • c-Jun N-terminal kinase kinase 1
  • dual specificity mitogen-activated protein kinase kinase 4
  • JNK activating kinase 1
  • JNK-activated kinase 1
  • JNK-activating kinase 1
  • JNKK
  • JNKK1
  • JNKK1MAPK/ERK kinase 4
  • MAP kinase kinase 4
  • MAP2K4
  • MAPKK4
  • MEK4
  • MEK4MEK 4
  • mitogen-activated protein kinase kinase 4
  • MKK4
  • MKK4SAPK/ERK kinase 1
  • PRKMK4
  • PRKMK4MAPKK 4
  • SEK1
  • SERK1
  • SERK1EC 2.7.12.2

Background

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Publications for MKK4/MEK4 Lysate (H00006416-T01) (0)

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Video Protocols

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Bioinformatics

Gene Symbol MAP2K4
Entrez