Menin Antibody

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Immunohistochemistry-Paraffin: Menin Antibody [NBP1-49896] - FFPE section of human prostate carcinoma. Antibody: Affinity purified mouse anti-Menin used at a dilution of 1:250. Detection: DAB staining using Goat ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-49896
    • Availability
      Product Discontinued

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Menin Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Clonality
Polyclonal
Host
Mouse
Gene
MEN1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Menin Antibody

  • MEAI
  • MEN1
  • Menin
  • multiple endocrine neoplasia I
  • multiple

Background

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the CDS. Five variants where alternative splicing takes place in the 5' UTR have also been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Menin Products

Bioinformatics Tool for Menin Antibody (NBP1-49896)

Discover related pathways, diseases and genes to Menin Antibody (NBP1-49896). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Menin Antibody (NBP1-49896)

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PTMs for Menin Antibody (NBP1-49896)

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Bioinformatics

Gene Symbol MEN1
Entrez