Melanophilin Antibody

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Western Blot: Melanophilin Antibody [NBP1-69185] - Titration: 0.2-1 ug/ml, Positive Control: Jurkat cell lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-69185
    • Availability
      Product Discontinued

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Melanophilin Antibody Summary

Immunogen
Synthetic peptides corresponding to MLPH (melanophilin) The peptide sequence was selected from the C terminal of MLPH. Peptide sequence NLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGK.
Clonality
Polyclonal
Host
Rabbit
Gene
MLPH
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against MLPH and was validated on Western blot.
Theoretical MW
66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Melanophilin Antibody

  • exophilin-3
  • l(1)-3Rk
  • l1Rk3
  • ln
  • melanophilin
  • MGC2771
  • MGC59733
  • SLAC2A
  • Slac-2a
  • SLAC2-A
  • Slp homolog lacking C2 domains a
  • Synaptotagmin-like protein 2a

Background

This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for Melanophilin Antibody (NBP1-69185)

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Bioinformatics

Gene Symbol MLPH
Uniprot