MEK1 Antibody


Western Blot: MEK1 Antibody [NBP1-00921] - Analysis of MEK1 (P293) antibody in extracts from HUVEC cells.
Immunohistochemistry: MEK1 Antibody [NBP1-00921] - Analyzes of MEK1 (P293) antibody in paraffin-embedded human brain tissue.

Product Details

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MEK1 Antibody Summary

Synthetic peptide, corresponding to amino acids 270-320 of Human MEK-1.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of MEK1 (P293) pAb in extracts from HUVEC cells.
Immunohistochemistry (IHC) analyzes of MEK1 (P293) pAb in paraffin-embedded human brain tissue.
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for MEK1 Antibody

  • dual specificity mitogen-activated protein kinase kinase 1
  • ERK activator kinase 1
  • MAP kinase kinase 1
  • MAP2K1
  • MAPK/ERK kinase 1
  • MAPKK1
  • MEK1
  • mitogen-activated protein kinase kinase 1
  • MKK1
  • MKK1MEK 1
  • protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)


A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Gene Symbol MAP2K1