MEF2A Antibody

Product Discontinued

MEF2A Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human MEF2A. The immunogen region is: C-terminal.
• Specificity: MEF2A (Ab-408) Antibody detects endogenous levels of total MEF2A protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MEF2A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:4000
  • Immunocytochemistry/ Immunofluorescence 1:100-1:500
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Western Blot 1:500-1:1000
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MEF2A Antibody

• ADCAD1
• MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancerfactor 2A)
• MEF2
• myocyte enhancer factor 2A
• myocyte-specific enhancer factor 2A
• RSRFC4
• RSRFC9
• Serum response factor-like protein 1

Background

MEF2A (myocyte specific enhancer factor 2) is a transcription factor protein that belongs to MEF2 family, a family of DNA binding regulatory proteins. MEF2 family members (MEF2A, 2B, 2C, and 2D) are highly expressed during dendritic maturation and synapse formation in the brain and are involved in the regulation of development and function of T-cell, muscle cells, and brain cells (1). Highly expressed during synaptogenesis, MEF2A binds to MEF2 element present in the regulatory regions in various muscle specific genes and activates transcription. MEF2A has been implicated in cardiac and skeletal muscle development (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MEF2A
• Entrez:
  • 4205(Human)
  • 17258(Mouse)
  • 309957(Rat)
• Uniprot:
  • Q02078(Human)