MEF2A [p Thr312] Antibody

Images

 
Western Blot: MEF2A [p Thr312] Antibody [NB100-92578] - Analysis of p-MEF2A (T312) antibody in extracts from NIH/3T3 cells.
Immunohistochemistry-Paraffin: MEF2A [p Thr312] Antibody [NB100-92578] - Paraffin-embedded human breast carcinoma tissue at 1:100.
Immunohistochemistry: MEF2A [p Thr312] Antibody [NB100-92578] - MEF2A Phosphospecific Antibody [NB100-92578] - Immunohistochemistry (IHC) analyzes of p-MEF2A (T312) antibody in paraffin-embedded human breast carcinoma ...read more

Product Details

Summary
Product Discontinued
View other related MEF2A Primary Antibodies

Order Details


    • Catalog Number
      NB100-92578
    • Availability
      Product Discontinued

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MEF2A [p Thr312] Antibody Summary

Immunogen
Synthetic phosphopeptide derived from human MEF-2 around the phosphorylation site of Threonine 312.
Modification
p Thr312
Specificity
p-MEF2A (T312) detects endogenous levels of p-MEF2A (T312) protein.
Clonality
Polyclonal
Host
Rabbit
Gene
MEF2A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NB100-92578 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MEF2A [p Thr312] Antibody

  • ADCAD1
  • MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancerfactor 2A)
  • MEF2
  • myocyte enhancer factor 2A
  • myocyte-specific enhancer factor 2A
  • RSRFC4
  • RSRFC9
  • Serum response factor-like protein 1

Background

MEF-2 is a muscle-specific DNA binding protein that recognizes an A+T-rich sequence [CTA (A/T)4 TAG] localized in the control regions of numerous muscle-specific genes. MEF-2 belongs to the MADS (MCM1, Agamous, Deficiens and serum-response factor) box family of transcription factors. The MEF-2 proteins arise from several alternatively spliced isoforms of the MEF-2 gene. MEF-2 expression is ubiquitous, but appears to be preferential in skeletal and cardiac muscle cells. Phosphorylation of different MEF-2C isoforms affects their expression pattern and transactivation function. Big MAP kinase 1 (BMK1) enhances the transactivation activity of MEF-2C by phosphorylating Ser 387. Serum is a potent stimulator of BMK1-induced MEF-2C phosphorylation. p38 MAPK can phosphorylate MEF-2C at positions Ser 387, Thr 293 and Thr 300. Phosphorylation of MEF-2C by either p38 MAPK or ERK5/BMK1 is necessary for Smad-MEF-2 signaling cooperativity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MEF2A Antibody (NB100-92578)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol MEF2A
Entrez
Uniprot