MCHR2 Antibody

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Western Blot: MCHR2 Antibody [NBP1-00916] - Western blot (WB) analysis of MCHR2 (M332) antibody in extracts from HUVEC cells

Product Details

Summary
Product Discontinued
View other related MCHR2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00916
    • Availability
      Product Discontinued

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MCHR2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 300-348 of Human MCH-2R.
Clonality
Polyclonal
Host
Rabbit
Gene
MCHR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
Application Notes
Western blot (WB) analysis of MCHR2 (M332) pAb in extracts from HUVEC cells.
Theoretical MW
39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MCHR2 Antibody

  • G protein-coupled receptor 145
  • G protein-coupled receptor slt
  • GPR145
  • GPRv17
  • MCH2MCHR-2
  • MCH-2R
  • MCH2RG-protein coupled receptor 145
  • MCHR2
  • MCH-R2
  • melanin-concentrating hormone 2
  • melanin-concentrating hormone receptor 2
  • SLT
  • SLTMCH receptor 2

Background

Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide,which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional MCHR2 Products

MCHR2 NBP1-00916

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Bioinformatics

Gene Symbol MCHR2
Entrez
Uniprot