MAPKAPK2 Antibody


Western Blot: MAPKAPK2 Antibody [NBP1-51331] - Extracts from COS cells.
Immunohistochemistry-Paraffin: MAPKAPK2 Antibody [NBP1-51331] - Paraffin-embedded human breast carcinoma tissue at 1:100.

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MAPKAPK2 Antibody Summary

Synthetic peptide, corresponding to amino acids 250-300 of Human MAPKAPK-2.
MAPKAPK-2 (N266) pAb detects endogenous levels of MAPKAPK-2 protein.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of MAPKAPK-2 (N266) pAb in extracts from COS cells.
Immunohistochemistry (IHC) analyzes of MAPKAPK-2 (N266) pAb in paraffin-embedded human breast carcinoma tissue.
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for MAPKAPK2 Antibody

  • EC 2.7.11
  • EC
  • MAP kinase-activated protein kinase 2
  • MAPK-activated protein kinase 2
  • MAPKAP kinase 2
  • mitogen-activated protein kinase-activated protein kinase 2
  • MK2
  • Rps6kc1


MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol MAPKAPK2