MAdCAM-1 Antibody (314G8) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-P
Clone
314G8
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

MAdCAM-1 Antibody (314G8) [DyLight 350] Summary

Immunogen
Recombinant soluble MAdCAM-1-fc fusion protein.
Localization
Membrane; single pass type I membrane protein.
Specificity
Recognizes human mucosal address in cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyer's patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MADCAM1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MAdCAM-1 Antibody (314G8) [DyLight 350]

  • hMAdCAM-1
  • MACAM1
  • MAdCAM1
  • MAdCAM-1
  • mucosal addressin cell adhesion molecule 1
  • mucosal addressin cell adhesion molecule-1
  • mucosal vascular addressin cell adhesion molecule 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-63263APC
Biotin Labeled NB100-63016
DyLight 405 Labeled NB100-63263V
DyLight 488 Labeled NB100-63263G
DyLight 680 Labeled NB100-63263FR
DyLight 755 Labeled NB100-63263IR
PE Labeled NB100-63263PE
PerCP Labeled NB100-63263PCP

Additional MAdCAM-1 Antibody (314G8) [DyLight 350] Products

MAdCAM-1 NB100-63263UV

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Bioinformatics

Gene Symbol MADCAM1
Entrez
Uniprot

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