MAdCAM-1 Antibody (314G8) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-P
Clone
314G8
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

MAdCAM-1 Antibody (314G8) [DyLight 488] Summary

Immunogen
Recombinant soluble MAdCAM-1-fc fusion protein.
Localization
Membrane; single pass type I membrane protein.
Specificity
Recognizes human mucosal address in cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyer's patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MADCAM1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MAdCAM-1 Antibody (314G8) [DyLight 488]

  • hMAdCAM-1
  • MACAM1
  • MAdCAM1
  • MAdCAM-1
  • mucosal addressin cell adhesion molecule 1
  • mucosal addressin cell adhesion molecule-1
  • mucosal vascular addressin cell adhesion molecule 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-63263APC
Biotin Labeled NB100-63016
DyLight 350 Labeled NB100-63263UV
DyLight 405 Labeled NB100-63263V
DyLight 680 Labeled NB100-63263FR
DyLight 755 Labeled NB100-63263IR
PE Labeled NB100-63263PE
PerCP Labeled NB100-63263PCP

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Bioinformatics Tool for MAdCAM-1 Antibody (NB100-63263G)

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Contact Information

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Bioinformatics

Gene Symbol MADCAM1
Entrez