Recombinant Human Macrophage Inflammatory Protein 1 alpha Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 24-92 of Human Macrophage Inflammatory Protein 1 alpha
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
| Protein/Peptide Type
>90%, by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
10mM Sodium Citrate (pH3.5) containing 10% glycerol
>90%, by SDS-PAGE
Alternate Names for Recombinant Human Macrophage Inflammatory Protein 1 alpha Protein
- C-C motif chemokine 3
- chemokine (C-C motif) ligand 3
- G0S19-1Tonsillar lymphocyte LD78 alpha protein
- Macrophage inflammatory protein 1-alpha
- MIP1AG0/G1 switch regulatory protein 19-1
- SCYA3PAT 464.1
- small inducible cytokine A3 (homologous to mouse Mip-1a)
- Small-inducible cytokine A3
CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner. Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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