Macrophage Inflammatory Protein 1 alpha Antibody Summary
Synthetic Peptide corresponding to aa 77-92 of human MIP-1a.
This product is specific for MIP-1 alpha
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:50
This product is specific for Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
10mM PBS (pH 7.4)
Immunogen affinity purified
Alternate Names for Macrophage Inflammatory Protein 1 alpha Antibody
- C-C motif chemokine 3
- chemokine (C-C motif) ligand 3
- G0S19-1Tonsillar lymphocyte LD78 alpha protein
- Macrophage inflammatory protein 1-alpha
- MIP1AG0/G1 switch regulatory protein 19-1
- SCYA3PAT 464.1
- small inducible cytokine A3 (homologous to mouse Mip-1a)
- Small-inducible cytokine A3
MIP1 alpha belongs to the chemokine beta family. In vitro MIP1 alpha stimulates H2O2 production in human neutrophils. MIP1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor 1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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