Macrophage Inflammatory Protein 1 alpha Antibody

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Immunohistochemistry-Paraffin: Macrophage Inflammatory Protein 1 alpha Antibody [NBP1-36112] Human Lung

Order Details


    • Catalog Number
      NBP1-36112
    • Availability
      Product Discontinued

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Macrophage Inflammatory Protein 1 alpha Antibody Summary

Immunogen
Synthetic Peptide corresponding to aa 77-92 of human MIP-1a.
Specificity
This product is specific for MIP-1 alpha
Clonality
Polyclonal
Host
Rabbit
Gene
CCL3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

This product is specific for Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4)
Preservative
Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Macrophage Inflammatory Protein 1 alpha Antibody

  • C-C motif chemokine 3
  • chemokine (C-C motif) ligand 3
  • G0S19-1Tonsillar lymphocyte LD78 alpha protein
  • LD78ALPHA
  • Macrophage inflammatory protein 1-alpha
  • MIP1AG0/G1 switch regulatory protein 19-1
  • MIP-1-alphaSIS-beta
  • SCYA3PAT 464.1
  • small inducible cytokine A3 (homologous to mouse Mip-1a)
  • Small-inducible cytokine A3

Background

MIP1 alpha belongs to the chemokine beta family. In vitro MIP1 alpha stimulates H2O2 production in human neutrophils. MIP1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor 1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCL3
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