Macro H2A.2 Antibody

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Western Blot: Macro H2A.2 Antibody [NBP1-52996] - Human Spleen lysate, concentration 0.2-1 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-52996
    • Availability
      Product Discontinued

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Macro H2A.2 Antibody Summary

Immunogen
Synthetic peptides corresponding to H2AFY2(H2A histone family, member Y2) The peptide sequence was selected from the middle region of H2AFY2. Peptide sequence PRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRT.
Clonality
Polyclonal
Host
Rabbit
Gene
H2AFY2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against H2AFY2 and was validated on Western blot.
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Macro H2A.2 Antibody

  • core histone macro-H2A.2
  • core histone macroH2A2.2
  • H2A histone family, member Y2
  • Histone macroH2A2
  • macroH2A2
  • mH2A2

Background

H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol H2AFY2
Uniprot