Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (8A1)

Images

 
Western Blot: JMJD2C Antibody (8A1) [NBP1-47816] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JMJD2C(Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunohistochemistry-Paraffin: JMJD2C Antibody (8A1) [NBP1-47816] Staining of paraffin-embedded prostate tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: JMJD2C Antibody (8A1) [NBP1-47816] - Staining of paraffin-embedded colon tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: JMJD2C Antibody (8A1) [NBP1-47816] - Staining of paraffin-embedded endometrium tissue using anti-JMJD2C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: JMJD2C Antibody (8A1) [NBP1-47816] - Staining of paraffin-embedded Kidney tissue using anti-JMJD2C mouse monoclonal antibody.

Order Details


    • Catalog Number
      NBP1-47816
    • Availability
      Product Discontinued

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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (8A1) Summary

Immunogen
Protein expressed in 293T cell transfected with human KDM4C expression vector
Specificity
This antibody is specific for Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KDM4C
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (8A1)

  • EC 1.14.11
  • EC 1.14.11.-
  • GASC-1 protein
  • GASC1
  • GASC1JmjC domain-containing histone demethylation protein 3C
  • Gene amplified in squamous cell carcinoma 1 protein
  • JHDM3C
  • JMJD2C
  • JMJD2CbA146B14.1
  • jumonji domain containing 2C
  • Jumonji domain-containing protein 2C
  • KDM4C
  • KIAA0780FLJ25949
  • Lysine (K)specific Demethylase 4C
  • Lysine (K)-specific Demethylase 4C
  • lysine-specific demethylase 4C

Background

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KDM4C
Entrez