Lyp/PTPN22 Antibody [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 525

Lyp/PTPN22 Antibody [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant human Lyp
  Ser306-Ser684
  Accession # Q9Y2R2
• Specificity: Detects human Lyp in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PTPN22
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lyp/PTPN22 Antibody [Janelia Fluor® 525]

• EC 3.1.3.48
• Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
• Lymphoid phosphatase
• lymphoid-specific protein tyrosine phosphatase
• Lyp
• Lyp1
• Lyp2
• LyPTP
• PEP
• PEST-domain phosphatase
• protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
• protein tyrosine phosphatase, non-receptor type 8
• PTPN22
• PTPN8 (former)
• PTPN8LYP1
• tyrosine-protein phosphatase non-receptor type 22

Background

PTPN22 encodes a protein tyrosine phosphatase which is expressed primarily in lymphoid tissues. This enzyme associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN22