LNK/SH2B3 Antibody (2C9)

Images

 
Western Blot: LNK Antibody (2C9) [NBP2-00774] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LNK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug ...read more
Immunocytochemistry/ Immunofluorescence: LNK Antibody (2C9) [NBP2-00774] Staining of COS7 cells transiently transfected by pCMV6-ENTRY LNK.
Flow Cytometry: LNK Antibody (2C9) [NBP2-00774] - Analysis of Jurkat cells, using anti-LNK antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Immunocytochemistry/ Immunofluorescence: LNK Antibody (2C9) [NBP2-00774] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-LNK ...read more
Flow Cytometry: LNK Antibody (2C9) [NBP2-00774] - Analysis of Hela cells, using anti-LNK antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-00774
    • Availability
      Product Discontinued

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LNK/SH2B3 Antibody (2C9) Summary

Immunogen
Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SH2B3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for LNK/SH2B3 Antibody (2C9)

  • IDDM20
  • LNK
  • LNKSH2B adapter protein 3
  • Lymphocyte adapter protein
  • Lymphocyte-specific adapter protein Lnk
  • SH2B adaptor protein 3
  • SH2B3
  • Signal transduction protein Lnk

Background

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional LNK/SH2B3 Products

Bioinformatics Tool for LNK/SH2B3 Antibody (NBP2-00774)

Discover related pathways, diseases and genes to LNK/SH2B3 Antibody (NBP2-00774). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for LNK/SH2B3 Antibody (NBP2-00774)

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Bioinformatics

Gene Symbol SH2B3
Entrez