LIM Kinase 1 Antibody

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Immunoprecipitation: LIM Kinase 1 Antibody [NBP1-42684] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-LIMK1 antibodyused for IP at 3 mcg/mg lysate. ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-42684
    • Availability
      Product Discontinued

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LIM Kinase 1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 250 and 300 of human LIM domain kinase 1 using the numbering given in entry NP_002305.1 (GeneID 3984).
Clonality
Polyclonal
Host
Rabbit
Gene
LIMK1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LIM Kinase 1 Antibody

  • EC 2.7.11.1
  • LIM domain kinase 1
  • LIM motif-containing protein kinase
  • LIMKLIMK-1

Background

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LIMK1
Entrez