Leptin/OB Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary
Applications PAGE
1 mg/ml

Order Details

Leptin/OB Recombinant Protein Summary

A recombinant protein corresponding to LEP.

Source: E. coli


Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Form : Liquid. In Phosphate buffered saline, pH 7.4.
1 mg/ml


Application Notes
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 16 kDa (147 aa), confirmed by MALDI-TOF.

Reactivity Notes


Alternate Names for Leptin/OB Recombinant Protein

  • FLJ94114
  • LEP
  • leptin (murine obesity homolog)
  • leptin (obesity homolog, mouse)
  • leptin
  • OB
  • Obese protein
  • obese, mouse, homolog of
  • Obesity factor


Human leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of using leptin as a therapeutic agent, are currently under intense investigation. Recombinant human leptin was overexpressed as insoluble protein aggregate in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol LEP

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