Recombinant Human LDL R Protein

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Product Details

Summary
Product Discontinued
View other related LDL R Peptides and Proteins

Order Details


    • Catalog Number
      H00003949-P01
    • Availability
      Product Discontinued

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Recombinant Human LDL R Protein Summary

Protein/Peptide Type
Recombinant Protein
Gene
LDLR

Applications/Dilutions

Application Notes
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells. This protein is not active and should not be used for experiments requiring activity.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human LDL R Protein

  • FH
  • FHC
  • LDL R
  • LDL receptor
  • LDLCQ2
  • LDLR
  • low density lipoprotein receptor
  • low-density lipoprotein receptor class A domain-containing protein 3
  • low-density lipoprotein receptor

Background

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. LDLR( AAH14514, 1 a.a. - 861 a.a.) recombinant protein with GST.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Additional LDL R Products

Bioinformatics Tool for LDL R Recombinant Protein (H00003949-P01)

Discover related pathways, diseases and genes to LDL R Recombinant Protein (H00003949-P01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for LDL R Recombinant Protein (H00003949-P01)

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Pathways for LDL R Recombinant Protein (H00003949-P01)

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PTMs for LDL R Recombinant Protein (H00003949-P01)

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Bioinformatics

Gene Symbol LDLR
Entrez