LDL R Antibody (C7) [Biotin]


There are currently no images for LDL R Antibody (NBP1-78159B).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity Hu, Rt, Po, BvSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Please see the vial label for concentration. If unlisted please contact technical services.

LDL R Antibody (C7) [Biotin] Summary

Partially purified bovine LDL receptor [Swiss-Prot# P01131]
Cell membrane/cell surface, endomembrane system, endosomes, lysosome, clathrin-coated pit, and Golgi apparatus
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
Biotin (A=N/A, E=N/A)
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
This LDL Receptor (C7) antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin embedded section, Immunoprecipitation and Western blot, where bands can be seen around 160 kDa (mature form) and 120 kDa (precursor). Radioimmunoassay and ELISA were reported in scientific literature.
Readout System

Alternate Names for LDL R Antibody (C7) [Biotin]

  • FH
  • FHC
  • LDL receptor
  • LDLCQ2
  • LDLR
  • low density lipoprotein receptor
  • low-density lipoprotein receptor class A domain-containing protein 3
  • low-density lipoprotein receptor


In cholesterol homeostasis regulation, the low density lipoprotein receptor is a critical factor. LDLR binds and internalizes LDL, then directs LDL toward cellular synthetic machinery, or towards destructive pathways for release or recycling. When alternatively spliced forms of the LDLR are present in cells, its native enzymatic activity is often reduced. This reduction in enzyme function is often related to the formation of atherosclerotic plaques. A common Class 5 mutation in LDLR results in it being able to bind and internalize LDL, but subsequently unable to release it to endosomes for recycling. LDLR is dependent upon the activity of PCSK9 for regulating its activity. In the liver, the LDLR is degraded when signaled by PCSK9, which increases the probability of high hepatic levels of LDL. In the brain, PCSK9 downregulates LDLR levels during development and following adult brain injury, thus demonstrating the dual functionality of this critical receptor.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP
Species: Hu
Applications: IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC
Species: Mu
Applications: WB, Simple Western
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Species: Hu, Ch
Applications: WB, ELISA, GS, ICC/IF, IP
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Ca, Ch, SyHa, Ha
Applications: WB, Simple Western
Species: Hu
Applications: WB, IHC

Publications for LDL R Antibody (NBP1-78159B) (0)

There are no publications for LDL R Antibody (NBP1-78159B).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for LDL R Antibody (NBP1-78159B) (0)

There are no reviews for LDL R Antibody (NBP1-78159B). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for LDL R Antibody (NBP1-78159B) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-78159APC
DyLight 350 Labeled NBP1-78159UV
DyLight 405 Labeled NBP1-78159V
DyLight 405LS Labeled NBP1-78159V3
DyLight 488 Labeled NBP1-78159G
DyLight 550 Labeled NBP1-78159R
DyLight 650 Labeled NBP1-78159C
DyLight 680 Labeled NBP1-78159FR
DyLight 755 Labeled NBP1-78159IR
FITC Labeled NBP1-78159F
HRP Labeled NBP1-78159H
PE Labeled NBP1-78159PE
PerCP Labeled NBP1-78159PCP

Additional LDL R Antibody (C7) [Biotin] Products

Related Products by Gene

Bioinformatics Tool for LDL R Antibody (NBP1-78159B)

Discover related pathways, diseases and genes to LDL R Antibody (NBP1-78159B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for LDL R Antibody (NBP1-78159B)

Discover more about diseases related to LDL R Antibody (NBP1-78159B).

Pathways for LDL R Antibody (NBP1-78159B)

View related products by pathway.

PTMs for LDL R Antibody (NBP1-78159B)

Learn more about PTMs related to LDL R Antibody (NBP1-78159B).

Research Areas for LDL R Antibody (NBP1-78159B)

Find related products by research area.

Blogs on LDL R

There are no specific blogs for LDL R, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol LDLR

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-78159B below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

LDL R Peptide